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Added to YB: 2025-09-30

Pitch date: 2025-09-27

GUTS [bullish]

Fractyl Health, Inc.

+60%

current return

Author Info

Anders Research shares equity research primarily focused on micro/small/mid-cap biotechnology. We follow companies with mechanistically differentiated approaches to large market opportunities, with special focus in neuroscience. Sign up for the newsletter.

Company Info

Fractyl Health, Inc., a metabolic therapeutics company, develops therapies for the treatment of type 2 diabetes (T2D) and obesity.

Market Cap

$200.1M

Pitch Price

$1.40

Price Target

N/A

Dividend

N/A

EV/EBITDA

-2.13

P/E

-0.63

EV/Sales

61.5K

Sector

Health Care Equipment and Supplies

Category

value

Show full summary:
Fractyl Health: Best-Case Results; Financing Dilutes But Removes Overhang

GUTS: Impressive REMAIN-1 results showed Revita patients lost additional 2.5% bodyweight 3mo post-GLP-1 discontinuation vs placebo gaining 10% (p=0.014). Best-case scenario validates metabolic reset hypothesis. Minimal side effects vs GLP-1s. $184M mkt cap/$80M EV significantly undervalued given massive market opportunity (10M GLP-1 users in 2025, 65-85% discontinue). Pivotal 315-patient data due 2H26, PMA filing follows.

Read full article (4 min)