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Added to YB: 2025-09-12

Pitch date: 2025-09-10

PTGX [bullish]

Protagonist Therapeutics, Inc.

+76.46%

current return

Author Info

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Company Info

Protagonist Therapeutics, Inc. operates as a discovery and development company in the United States. It develops Icotyde, a first-in-class investigational targeted oral peptide for the treatment of adults and pediatric patients 12 years of age and older with moderate-to-severe plaque psoriasis; and Rusfertide, a first-in-class investigational injectable mimetic of the natural hormone hepcidin in Phase 3 development for the treatment of the rare blood disorder polycythemia vera.

Market Cap

$6.7B

Pitch Price

$57.81

Price Target

173.00 (+70%)

Dividend

N/A

EV/EBITDA

-43.75

P/E

-57.99

EV/Sales

81.96

Sector

Biotechnology

Category

growth

Show full summary:
PTGX: A JNJ bond trading below face value with free call options attached!

PTGX: Oral IL-23 drug Icotrokinra (JNJ partner) showing superior efficacy vs injectables in psoriasis/UC, targeting $15B+ market. JNJ guides 2x consensus at $1.4B 2028 sales. 6-10% royalties could yield $400-900M annually. Rusfertide (Takeda) approval H2 2026, opt-out pays $400M. Pipeline includes oral IL-17 (LLY paid $2.4B for similar asset). Base case $67.5/share on approved drugs alone, current $58.

Read full article (18 min)